Abbkine Scientific Co., Ltd.
PRP100398
$370.00
20µg
| 20µg - | $370.00 | |
| 100µg - | $1,450.00 |
Mouse IL-13 protein
Fig.SDS-PAGE analysis of Mouse IL-13 protein.Antigen:
Aliases:Il-13; Interleukin-13; IL13
Description:
Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses and diseases. In addition, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody is more importantly implicated as a central mediator of immunoregulatory processes in various cell types.
Preparation method:Human; Cells
Activity:
Measured in a cell proliferation assay using TF1 human erythroleukemic cells (Kitamura, T. et al. (1989) J. Cell Physiol. 140:323.).
The ED50 for this effect is typically 2-10 ng/mL.
Formulation:Lyophilized from sterile PBS, pH 7.5
Storage conditions:Lyophilized Mouse IL13 protein product should be stored desiccated below -18°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Delivery conditions:The product is shipped at ambient temperature.
Usage:
Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Mouse IL13 protein in sterile ddH2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Purity:> 90 % as determined by SDS-PAGE
Molecular weight:12.1
Sequence:Amino acid sequence derived from mouse IL13 (P20109) (Pro22-Phe131) was expressed and purified.
Protein length:The recombinant mouse IL13 consists of 110 amino acids and predicts a molecular mass of 12.1 KDa. It migrates as an approximately 14 KDa band in SDS-PAGE under reducing conditions.
Precautions:
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Others:The Endotoxin level is less than 1.0 EU per μg of the protein as determined by the LAL method