IκB-α Polyclonal Antibody
Fig. Western Blot analysis of various cells using IκB-α Polyclonal Antibody.
Antigen:NF-kappa-B inhibitor alphaSynonyms: I-kappa-B-alpha; Major histocompatibility complex enhancer-binding protein MAD3; IKBA_HUMAN; B2R8L6; P25963
Reactivity:Human; Mouse; Rat Application:Western Blotting; IHC-P; Immunofluorescence; ELISA Description:Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:10000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Precautions:The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Alternative:NFKBIA
IKBA
MAD3
NFKBI
NF-kappa-B inhibitor alpha
I-kappa-B-alpha
IkB-alpha
IkappaBalpha
Major histocompatibility complex enhancer-binding protein MAD3
Storage conditions:Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Delivery conditions:Gel pack with blue ice. Immunogen:Synthesized peptide derived from human IκB-α around the non-phosphorylation site of Y42. Usage:NFKBIA encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. NF-kappa-B inhibitor alpha interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. NF-kappa-B inhibitor alpha moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.