Abbkine Scientific Co., Ltd.
ABP50799
$100.00
30μl
| 30μl - | $100.00 | |
| 100μl - | $220.00 | |
| 200μl - | $360.00 |
Btk Polyclonal Antibody
Fig.1. Western Blot analysis of various cells using Btk Polyclonal Antibody diluted at 1:500....
Fig.2. Western Blot analysis of 293 cells using Btk Polyclonal Antibody diluted at 1:500....Antigen:
Tyrosine-protein kinase BTK
Synonyms: Agammaglobulinemia tyrosine kinase; B-cell progenitor kinase; Bruton tyrosine kinase; BTK_HUMAN; B2RAW1; Q06187; Q32ML5
Host:Rabbit
Reactivity:Human; Mouse; Rat; Monkey
Application:Western Blotting; IHC-P; ELISA
Isotype:IgG
Clonality:Polyclonal
Description:
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation:Liquid solution
Precautions:
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Alternative:
BTK
AGMX1
ATK
BPK
Tyrosine-protein kinase BTK
Agammaglobulinaemia tyrosine kinase
ATK
B-cell progenitor kinase
BPK
Bruton tyrosine kinase
Buffer form:PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage conditions:Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Delivery conditions:Gel pack with blue ice.
Immunogen:Synthesized peptide derived from human Btk around the non-phosphorylation site of Y223.
Usage:
The protein(Bruton tyrosine kinase)encoded by BTK plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
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