Abbkine Scientific Co., Ltd.
ABP57290
$100.00
30μl
| 30μl - | $100.00 | |
| 100μl - | $220.00 | |
| 200μl - | $360.00 |
Bcl-Xl Polyclonal Antibody
Fig. Immunohistochemical analysis of paraffin-embedded Human Lung Carcinoma using Bcl-XlRabbit...Antigen:
Bcl-2-like protein 1
Synonyms: Apoptosis regulator Bcl-X; B2CL1_HUMAN; E1P5L6; Q07817; Q5CZ89; Q5TE65; Q92976
Host:Rabbit
Reactivity:Human; Mouse; Rat
Application:IHC-P
Isotype:IgG
Clonality:Polyclonal
Description:
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-p: 1:50-1:200.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation:Liquid solution
Precautions:
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Buffer form:PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Storage conditions:Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Delivery conditions:Gel pack with blue ice.
Immunogen:Recombinant Protein
Usage:
The protein encoded by BCL2L1 （BCL2 like 1)belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.
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