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Abbkine Scientific Co., Ltd.:

Abbkine Scientific Co., Ltd was founded in 2012 in California. The company quickly expands to China, where its headquarters are located now. Abbkine offers experimental kits, proteins, antibodies, proteomics and cytology reagents. Created by scientists and marketing experts, Abbkine helps progress in human and animal health.

Antibodies
(11570)
ELISA Kits
(6601)
Protein Biochemistry
(120)
Cell biology
(104)
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(90)
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(79)
Aliases:Flag Resin
PurKine™ Anti-DDDDK Resin 4FF has been designed for affinity purification of DDDDK fusion proteins. The Resin consists of 90μm beads of cross-linked 4% agarose, to which mouse monoclonal antibody against DYKDDDDK tag has been coupled. The portfolio allow optimization of process for maximum protein yield, stability and solubility. Tests also confirm that no decrease in performance occurs after at least five repeated uses. The PurKine™ Anti-DDDDK Resin 4FF is also available as prepacked spin column and kit formats.
1ml$1,360.00
5ml$5,440.00
50ml$43,520.00
Aliases:Protein AT; Protein AT resin; Protein Alkaline Tolerate
PurKine™ Protein AT Purification system is effective for affinity purification of monoclonal antibodies at process scale. Protein At is an alkali-resistant protein A (Alkaline tolerate) based on the native protein A though biotechnology mutation. This ligand provides greater stability than conventional protein A, and cleaning can be performed with cost-effective reagents such as sodium hydroxide eliminating the need for expensive and hazardous cleaning agents. The portfolio allow optimization of process for maximum protein yield, stability and solubility. Tests also confirm that no decrease in performance occurs after at least five repeated uses. The PurKine™ Protein AT Purification Resin is also available as prepacked spin column and kit formats.
1ml×5$894.00
3ml×5$2,146.00
Aliases:Protein L; Protein L resin
PurKine™ Protein L Purification system is effective for affinity purification of mammalian IgG that contain specific kappa light chains from serum, ascites fluid, cell culture supernantant and other antibody samples. Recombinant Protein L is chemically modified with a proprietary method to minimize nonspecific binding of proteins. Protein L is extremely useful for purification of VLk-containing monoclonal antibodies from culture supernatant because it does not bind bovine immunoglobilins, which are present in the media serum supplement. The portfolio allow optimization of process for maximum protein yield, stability and solubility. Tests also confirm that no decrease in performance occurs after at least five repeated uses. The PurKine™ Protein L Purification Resin is also available as prepacked spin column and kit formats.
1ml×5$632.00
3ml×5$1,516.00
Aliases:Protein L; Protein L resin
PurKine™ Protein L Purification system is effective for affinity purification of mammalian IgG that contain specific kappa light chains from serum, ascites fluid, cell culture supernantant and other antibody samples. Recombinant Protein L is chemically modified with a proprietary method to minimize nonspecific binding of proteins. Protein L is extremely useful for purification of VLk-containing monoclonal antibodies from culture supernatant because it does not bind bovine immunoglobilins, which are present in the media serum supplement. The portfolio allow optimization of process for maximum protein yield, stability and solubility. Tests also confirm that no decrease in performance occurs after at least five repeated uses. The PurKine™ Protein L Purification Resin is also available as prepacked spin column and kit formats.
1ml×5$578.00
3ml×5$1,388.00
PurKine™ Protein G Purification system is effective for affinity purification of IgG from serum and other fluids of many mammalian species. Protein G can be used for purification of mammalian monoclonal and polyclonal IgGs that do not bind well to protein A. Protein G has greater affinity than protein A for most mammalian IgGs, especially for certain subclasses including human IgG3, mouse IgG1 and rat IgG2a. Unlike protein A, protein G does not bind to human IgM, IgD and IgA. The portfolio allow optimization of process for maximum protein yield, stability and solubility. Tests also confirm that no decrease in performance occurs after at least five repeated uses. The PurKine™ Protein G Purification Resin is also available as prepacked spin column and kit formats.
1ml×5$568.00
3ml×5$1,364.00
Aliases:Dylight 350
AbFluor™ 350 is a new type of blue fluorescent dye. Compared with the traditional blue fluorescent dye AMCA, AbFluor™ 350 has better water-soluble, stronger light stability, higher fluorescence intensity. In addition, the fluorescence intensity of AbFluor™ 350 can be comparable to those of Alexa Fluor350 and the light resistance of AbFluor™ 350 is better. AbFluor™ 350 can replace Alexa Fluor 350.
5mg$560.00
50mg$4,480.00
Aliases:Dylight 405
AbFluor™ 405S is a kind of blue fluorescent dye. Its absorption peak wavelength is completely match 405 nm blue laser diode, and the emission peak wavelength of AbFluor™ 405S is just in the middle of BD Flow cytometry blue detection channel. Therefore, in the Flow analysis, AbFluor™ 405S dye presents stronger fluorescent signal than Alexa Flour 405.
5mg$560.00
50mg$4,480.00
Aliases:Dylight 488
AbFluor™ 488 free acid is a kind of green fluorescent dye with super brightness. It owns excellent solubility in water. Its pH sensitive range is between pH 4 to 10, which is an ideal substitute of FITC.
5mg$560.00
50mg$4,480.00
AbFluor™ 532 is an excellent orange fluorescent dye with the maximum absorption and emission wavelength in 527 and 558 nm. Compared with the traditional orange fluorescent dye like Alexa Fluor 532, AbFluor™ 532 has better water-soluble, stronger light stability, higher fluorescence intensity.
5mg$560.00
50mg$4,480.00
Aliases:Dylight 594
AbFluor™ 594 free acid is a bright, red-fluorescent dye similar to Alexa Fluor® 594 and Texas Red. Due to its higher quantum yield and excellent water solubility, AbFluor™ 594 free shows brighter fluorescent compared to Alexa Fluor® 594. In addition, AbFluor™ 594 free acid has good light stability, which can be used for laser confocal and single molecular imaging. AbFluor™ 594 free acid is the best choice for labeling protein and nucleic acid.
5mg$560.00
50mg$4,480.00
AbFluor™ 633 is a far infrared fluorescent dye, which has bright fluorescence and strong light stability. The absorption peak of AbFluor™ 633 is 630 nm, which can be best match of 633 nm hene laser or 635 nm red diode laser. The emission peak of AbFluor™ 633 is 650 nm. AbFluor™ 633 is brighter than other dyes. In addition, the more important advantage of AbFluor™ 633 is its incomparable light stability. AbFluor™ 633 is the best choice for equipment with 633 nm or 650 nm laser excitation system.
5mg$560.00
50mg$4,480.00
AbFluor™ 647 free acid is a kind red-fluorescent dye. It can produce bright fluorescence. The most distinct feature of the AbFluor™ 647 free acid is its superior signal-to-noise ratio of combination of antibody in immune fluorescence reaction. At the same time, compared with Alexa Fluor 647, AbFluor™ 647 free acid has few charge, which will not affect the specificity of the antibodies combination. So it is an ideal fluorescent dye.
5mg$560.00
50mg$4,480.00
AbFluor™ 555 free acid is a kind of orange red fluorescent dye, and is very similar to the Cy ™ 3 dye. When combined with protein, AbFluor™ 555 free acid is easier to imaging than Cy ™ 3, and brighter fluorescence. AbFluor™ 555 Free acid has good solubility in water and pH insensitivity. It is an ideal fluorescent dye.
5mg$560.00
50mg$4,480.00
AbFluor™ 660 free acid is a kind of fluorescent dye which is critical in far infrared and near infrared spectral range. The emission wavelength is at about 685 nm. Though the maximum absorption wavelength of AbFluor™ 660 free acid is at 660 nm, it can be excited by 633 or 635 nm laser. Compared with the Alexa Fluor660 dye, AbFluor™ 660 free acid can produce brighter fluorescence, and have better light stability, so it is the ideal dye for laser confocal and single molecular imaging.
5mg$560.00
50mg$4,480.00
Aliases:Dylight 680
AbFluor™ 680 free acid is an excellent near infrared fluorescent dye which can produce bright fluorescence, and has good light stability. It is the ideal dye for laser confocal and single molecular imaging.
5mg$560.00
50mg$4,480.00
PurKine™ Protein A/G Purification system is effective for affinity purification of IgG from serum, ascites fluid, cell culture supernantant and other antibody samples. Recombinant Protein A/G is chemically modified with a proprietary method to minimize nonspecific binding of proteins. Also, Protein A/G binding to immunoglobulins is not as pH-dependant as Protein A. Protein A/G binds to all human IgG subclasses and binds well to all mouse IgG subclasses but does not bind mouse IgA, IgM or serum albumin. The portfolio allow optimization of process for maximum protein yield, stability and solubility. Tests also confirm that no decrease in performance occurs after at least five repeated uses. The PurKine™ Protein A/G Purification Resin is also available as prepacked spin column and kit formats.
1ml×5$546.00
3ml×5$1,310.00
Antigen:
Transforming growth factor beta-1 proprotein
Synonyms: TGFB1_HUMAN; A8K792; P01137; Q9UCG4
Aliases:CED; DPD1; LAP; TGF-beta 1; TGFB; TGFbeta; Transforming growth factor beta-1; TGFB1
Preparation method:Human; Cells
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, differentiation, motility, adhesion and death. TGF-beta 1 positively and negatively regulates many other growth factors. It inhibits the secretion and activity of many other cytokines including interferon-γ, tumor necrosis factor-alpha and various interleukins. It can also decrease the expression levels of cytokine receptors. Meanwhile, TGF-beta 1 also increases the expression of certain cytokines in T cells and promotes their proliferation, particularly if the cells are immature. TGF-beta 1 also inhibits proliferation and stimulates apoptosis of B cells, and plays a role in controlling the expression of antibody, transferrin and MHC class II proteins on immature and mature B cells. As for myeloid cells, TGF-beta 1can inhibit their proliferation and prevent their production of reactive oxygen and nitrogen intermediates. However, as with other cell types, TGF-beta 1 also has the opposite effect on cells of myeloid origin. TGF-beta 1 is a multifunctional protein that controls proliferation, differentiation and other functions in many cell types. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Once cells lose their sensitivity to TGF-beta1-mediated growth inhibition, autocrine TGF-beta signaling can promote tumorigenesis. Elevated levels of TGF-beta1 are often observed in advanced carcinomas, and have been correlated with increased tumor invasiveness and disease progression.
10µg$510.00
20µg$829.00
50µg$1,430.00
PurKine™ Biotin-Tag Purification system is based on innovative high-capacity matrix for convenient single-step purification of biotin and biotinylated substances. Biotinylated antibodies, proteins, peptides, nucleic acids and other molecules or interaction complexes can be captured, immunoprecipitated, removed or purified from samples using this streptavidin resin. The portfolio allow optimization of process for maximum protein yield, stability and solubility. Tests also confirm that no decrease in performance occurs after at least five repeated uses. The PurKine™ Biotin-Tag Purification resin is also available as prepacked spin column and kit formats.
1ml×5$474.00
3ml×5$1,138.00
PurKine™ Protein A Purification system is designed for easy, one-step purification of classes, subclasses and fragments of immunoglobulins from biological fluids and from cell culture media. Recombinant protein A is produced in E. coli and functions essentially the same as native Protein A from Staphylococcus aureus. The Protein A molecule contains four high-affinity binding sites capable of interacting with the Fc region from IgG of several species. Protein A is generally preferred for affinity purification of rabbit, Guinea pig, dog and cat IgG. The portfolio allow optimization of process for maximum protein yield, stability and solubility. Tests also confirm that no decrease in performance occurs after at least five repeated uses. The PurKine™ Protein A Purification Resin is also available as prepacked spin column and kit formats.
1ml×5$418.00
3ml×5$1,004.00
Antigen:
Interleukin-8
Synonyms: C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1; Monocyte-derived neutrophil chemotactic factor; Monocyte-derived neutrophil-activating peptide; Neutrophil-activating protein 1; Protein 3-10C; T-cell chemotactic factor; IL8_HUMAN; B2R4L8; P10145; Q6FGF6; Q6LAE6; Q96RG6; Q9C077; Q9UCE1; Q9UCR8; Q9UCR9; Q9UCS0
Aliases:GCP-1; GCP1; IL-8; IL8; Interleukin-8; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; Interleukin-8; CXCL8
Preparation method:Human; Cells
Interleukin 8 (IL-8), also known as CXCL8, which is a chemokine with a defining CXC amino acid motif that was initially characterized for its leukocyte chemotactic activity, is now known to possess tumorigenic and proangiogenic properties as well. This chemokine is secreted by a variety of cell types including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, and various tumor cell lines in response to inflammatory stimuli (IL1, TNF, LPS, etc). In human gliomas, IL-8 is expressed and secreted at high levels both in vitro and in vivo, and recent experiments suggest it is critical to glial tumor neovascularity and progression. Levels of IL-8 correlate with histologic grade in glial neoplasms, and the most malignant form, glioblastoma, shows the highest expression in pseudopalisading cells around necrosis, suggesting that hypoxia/anoxia may stimulate expression. Interleukin (IL)-8/CXCL8 is a potent neutrophil chemotactic factor. Accumulating evidence has demonstrated that various types of cells can produce a large amount of IL-8/CXCL8 in response to a wide variety of stimuli, including proinflammatory cytokines, microbes and their products, and environmental changes such as hypoxia, reperfusion, and hyperoxia. Numerous observations have established IL-8/CXCL8 as a key mediator in neutrophil-mediated acute inflammation due to its potent actions on neutrophils. However, several lines of evidence indicate that IL-8/CXCL8 has a wide range of actions on various types of cells, including lymphocytes, monocytes, endothelial cells, and fibroblasts, besides neutrophils. The discovery of these biological functions suggests that IL-8/CXCL8 has crucial roles in various pathological conditions such as chronic inflammation and cancer. IL-8 has been associated with tumor angiogenesis, metastasis, and poor prognosis in breast cancer. IL-8 may present a novel therapeutic target for estrogen driven breast carcinogenesis and tumor progression.
50µg$410.00
100µg$720.00
Antigen:
Interleukin-36 receptor antagonist protein
Synonyms: FIL1 delta; IL-1-related protein 3; Interleukin-1 HY1; Interleukin-1 delta; Interleukin-1 family member 5; Interleukin-1 receptor antagonist homolog 1; Interleukin-1-like protein 1; I36RA_HUMAN; A8K2I4; Q56AT9; Q7RTZ6; Q9UBH0
Aliases:C7; crg-2; gIP-10; IFI10; INP10; IP-10; mob-1; SCYB10; Interleukin-36 receptor antagonist protein; CXCL10
Preparation method:Escherichia coli
CXCL10, also known as crg-2, is a chemokine of the CXC subfamily and ligand for the receptor CXCR3. CXC chemokines are particularly significant for leukocyte infiltration in inflammatory diseases. CXCL10 has a three-dimensional crystal structure. Its signaling is mediated by the g protein-coupled receptor CXCR3, which is expressed on activated T cells and plays an important role in directing the migration of T cells, especially during Th1 responses. Binding of CXCL10 to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. It is chemotactic for monocytes and T-lymphocytes. CXCL10 can be secreted by several cell types in response to IFN-γ. Baseline pre-treatment plasma levels of CXCL10 are elevated in patients chronically infected with hepatitis C virus (HCV) of genotypes 1 or 4 who do not achieve a sustained viral response (SVR) after completion of antiviral therapy.
50µg$410.00
100µg$720.00
Antigen:
Aliases:Transforming growth factor beta-1; TGFB1
Preparation method:Human; Cells
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, differentiation, motility, adhesion and death. TGF-beta 1 positively and negatively regulates many other growth factors. It inhibits the secretion and activity of many other cytokines including interferon-γ, tumor necrosis factor-alpha and various interleukins. It can also decrease the expression levels of cytokine receptors. Meanwhile, TGF-beta 1 also increases the expression of certain cytokines in T cells and promotes their proliferation, particularly if the cells are immature. TGF-beta 1 also inhibits proliferation and stimulates apoptosis of B cells, and plays a role in controlling the expression of antibody, transferrin and MHC class II proteins on immature and mature B cells. As for myeloid cells, TGF-beta 1can inhibit their proliferation and prevent their production of reactive oxygen and nitrogen intermediates. However, as with other cell types, TGF-beta 1 also has the opposite effect on cells of myeloid origin. TGF-beta 1 is a multifunctional protein that controls proliferation, differentiation and other functions in many cell types. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Once cells lose their sensitivity to TGF-beta1-mediated growth inhibition, autocrine TGF-beta signaling can promote tumorigenesis. Elevated levels of TGF-beta1 are often observed in advanced carcinomas, and have been correlated with increased tumor invasiveness and disease progression.
5µg$410.00
20µg$1,030.00
Antigen:
Aliases:Transforming growth factor beta-1; TGFB1
Preparation method:Human; Cells
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, differentiation, motility, adhesion and death. TGF-beta 1 positively and negatively regulates many other growth factors. It inhibits the secretion and activity of many other cytokines including interferon-γ, tumor necrosis factor-alpha and various interleukins. It can also decrease the expression levels of cytokine receptors. Meanwhile, TGF-beta 1 also increases the expression of certain cytokines in T cells and promotes their proliferation, particularly if the cells are immature. TGF-beta 1 also inhibits proliferation and stimulates apoptosis of B cells, and plays a role in controlling the expression of antibody, transferrin and MHC class II proteins on immature and mature B cells. As for myeloid cells, TGF-beta 1can inhibit their proliferation and prevent their production of reactive oxygen and nitrogen intermediates. However, as with other cell types, TGF-beta 1 also has the opposite effect on cells of myeloid origin. TGF-beta 1 is a multifunctional protein that controls proliferation, differentiation and other functions in many cell types. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Once cells lose their sensitivity to TGF-beta1-mediated growth inhibition, autocrine TGF-beta signaling can promote tumorigenesis. Elevated levels of TGF-beta1 are often observed in advanced carcinomas, and have been correlated with increased tumor invasiveness and disease progression.
5µg$410.00
20µg$1,030.00
Aliases:Protein G; Protein G resin
PurKine™ Protein G Purification system is effective for affinity purification of IgG from serum and other fluids of many mammalian species. Protein G can be used for purification of mammalian monoclonal and polyclonal IgGs that do not bind well to protein A. Protein G has greater affinity than protein A for most mammalian IgGs, especially for certain subclasses including human IgG3, mouse IgG1 and rat IgG2a. Unlike protein A, protein G does not bind to human IgM, IgD and IgA. The portfolio allow optimization of process for maximum protein yield, stability and solubility. Tests also confirm that no decrease in performance occurs after at least five repeated uses. The PurKine™ Protein G Purification Resin is also available as prepacked spin column and kit formats.
1ml×5$406.00
3ml×5$974.00
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