Antigen
TGFB1
Isotype
IgG
(5)
IgG1
(4)
Reactivity
Human
(8)
Mouse
(7)
Rat
(7)
Preparation method
Cells
(1)
CHO
(1)
Human
(1)
Stable Cells
(1)
Clonality
Polyclonal
(5)
Monoclonal
(4)
Application
Western Blotting
(7)
ELISA
(5)
IHC-P
(4)
Immunohistochemistry
(2)
FCM
(1)
Immunofluorescence
(1)
Supplier
Abbkine Scientific Co., Ltd.
(15)
Affinity Biosciences
(3)
Host
Rabbit
(5)
Mouse
(4)
Category
Antibodies
(9)
ELISA Kits
(7)
Cell biology
(2)
Immunochemicals
(2)
Protein Biochemistry
(2)
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Antigen:
Transforming growth factor beta-1 proprotein
Synonyms: TGFB1_HUMAN; A8K792; P01137; Q9UCG4
Aliases:CED; DPD1; LAP; TGF-beta 1; TGFB; TGFbeta; Transforming growth factor beta-1; TGFB1
Preparation method:Human; Cells
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, differentiation, motility, adhesion and death. TGF-beta 1 positively and negatively regulates many other growth factors. It inhibits the secretion and activity of many other cytokines including interferon-γ, tumor necrosis factor-alpha and various interleukins. It can also decrease the expression levels of cytokine receptors. Meanwhile, TGF-beta 1 also increases the expression of certain cytokines in T cells and promotes their proliferation, particularly if the cells are immature. TGF-beta 1 also inhibits proliferation and stimulates apoptosis of B cells, and plays a role in controlling the expression of antibody, transferrin and MHC class II proteins on immature and mature B cells. As for myeloid cells, TGF-beta 1can inhibit their proliferation and prevent their production of reactive oxygen and nitrogen intermediates. However, as with other cell types, TGF-beta 1 also has the opposite effect on cells of myeloid origin. TGF-beta 1 is a multifunctional protein that controls proliferation, differentiation and other functions in many cell types. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Once cells lose their sensitivity to TGF-beta1-mediated growth inhibition, autocrine TGF-beta signaling can promote tumorigenesis. Elevated levels of TGF-beta1 are often observed in advanced carcinomas, and have been correlated with increased tumor invasiveness and disease progression.
10µg$510.00
20µg$829.00
50µg$1,430.00
Test method:Colorimetric
TGF-β is capable of producing a variety of effects and virtually all cell types respond to this factor in some way. The inappropriate presence of active TGF-β1 has been implicated in a variety of pathological conditions Because of the necessity for regulating its activity tightly, TGF-β is secreted by cells in the form of an inactive complex. This complex consists of TGF-β1 associated non-covalently with a protein designated the latency associated peptide (LAP). TGF-β1 and LAP represent components of a pro-peptide that is cleaved in a post-golgi compartment prior to secretion. LAP and TGF-β1 each consist of a disulfide-linked homodimer and the association of these two components renders TGF-β1 inactive and inaccessible to anti-TGF-β antibodies.
48T$310.00
96T$580.00
96T*5$2,610.00
96T*50$23,200.00
Antigen:
Transforming growth factor beta-1 proprotein
Synonyms: TGFB1_PIG; K7GQZ2; P07200; P08832
Test method:Colorimetric
TGF-β is capable of producing a variety of effects and virtually all cell types respond to this factor in some way. The inappropriate presence of active TGF-β1 has been implicated in a variety of pathological conditions Because of the necessity for regulating its activity tightly, TGF-β is secreted by cells in the form of an inactive complex. This complex consists of TGF-β1 associated non-covalently with a protein designated the latency associated peptide (LAP). TGF-β1 and LAP represent components of a pro-peptide that is cleaved in a post-golgi compartment prior to secretion. LAP and TGF-β1 each consist of a disulfide-linked homodimer and the association of these two components renders TGF-β1 inactive and inaccessible to anti-TGF-β antibodies.
48T$305.00
96T$570.00
96T*5$2,565.00
96T*50$22,800.00
Antigen:
Transforming growth factor beta-1 proprotein
Synonyms: TGFB1_HUMAN; A8K792; P01137; Q9UCG4
Host:Rabbit
Reactivity:Human; Mouse; Rat
Application:Western Blotting; Immunohistochemistry; ELISA
Isotype:IgG
Clonality:Polyclonal
Aliases:Cartilage-inducing factor; CED; Differentiation inhibiting factor; DPD1; LAP; Latency-associated peptide; Prepro transforming growth factor beta 1; TGF beta 1; TGF beta; TGF beta 1 protein; TGF-beta 1 protein; TGF-beta-1; TGF-beta-5; TGF-beta1; TGFB; Tgfb-1; tgfb1; TGFB1_HUMAN; TGFbeta; TGFbeta1; Transforming Growth Factor b1; Transforming Growth Factor beta 1; Transforming growth factor beta 1a; transforming growth factor beta-1; transforming growth factor, beta 1; Transforming Growth Factor-ß1
100μl$280.00
200μl$350.00
Test method:Colorimetric
TGF-β is capable of producing a variety of effects and virtually all cell types respond to this factor in some way. The inappropriate presence of active TGF-β1 has been implicated in a variety of pathological conditions Because of the necessity for regulating its activity tightly, TGF-β is secreted by cells in the form of an inactive complex. This complex consists of TGF-β1 associated non-covalently with a protein designated the latency associated peptide (LAP). TGF-β1 and LAP represent components of a pro-peptide that is cleaved in a post-golgi compartment prior to secretion. LAP and TGF-β1 each consist of a disulfide-linked homodimer and the association of these two components renders TGF-β1 inactive and inaccessible to anti-TGF-β antibodies.
48T$280.00
96T$480.00
96T*5$2,160.00
96T*50$20,160.00
Antigen:
Transforming growth factor beta-1 proprotein
Synonyms: TGFB1_HUMAN; A8K792; P01137; Q9UCG4
Test method:Colorimetric
TGF-β is capable of producing a variety of effects and virtually all cell types respond to this factor in some way. The inappropriate presence of active TGF-β1 has been implicated in a variety of pathological conditions Because of the necessity for regulating its activity tightly, TGF-β is secreted by cells in the form of an inactive complex. This complex consists of TGF-β1 associated non-covalently with a protein designated the latency associated peptide (LAP). TGF-β1 and LAP represent components of a pro-peptide that is cleaved in a post-golgi compartment prior to secretion. LAP and TGF-β1 each consist of a disulfide-linked homodimer and the association of these two components renders TGF-β1 inactive and inaccessible to anti-TGF-β antibodies.
48T$280.00
96T$480.00
96T*5$2,160.00
96T*50$20,160.00
Antigen:
Test method:Colorimetric
TGF-β is capable of producing a variety of effects and virtually all cell types respond to this factor in some way. The inappropriate presence of active TGF-β1 has been implicated in a variety of pathological conditions Because of the necessity for regulating its activity tightly, TGF-β is secreted by cells in the form of an inactive complex. This complex consists of TGF-β1 associated non-covalently with a protein designated the latency associated peptide (LAP). TGF-β1 and LAP represent components of a pro-peptide that is cleaved in a post-golgi compartment prior to secretion. LAP and TGF-β1 each consist of a disulfide-linked homodimer and the association of these two components renders TGF-β1 inactive and inaccessible to anti-TGF-β antibodies.
48T$280.00
96T$480.00
96T*5$2,160.00
96T*50$20,160.00
Antigen:
Transforming growth factor beta-1 proprotein
Synonyms: TGFB1_CHICK; A0A1D5PM67; P09531
Test method:Colorimetric
TGF-β is capable of producing a variety of effects and virtually all cell types respond to this factor in some way. The inappropriate presence of active TGF-β1 has been implicated in a variety of pathological conditions Because of the necessity for regulating its activity tightly, TGF-β is secreted by cells in the form of an inactive complex. This complex consists of TGF-β1 associated non-covalently with a protein designated the latency associated peptide (LAP). TGF-β1 and LAP represent components of a pro-peptide that is cleaved in a post-golgi compartment prior to secretion. LAP and TGF-β1 each consist of a disulfide-linked homodimer and the association of these two components renders TGF-β1 inactive and inaccessible to anti-TGF-β antibodies.
48T$260.00
96T$480.00
96T*5$2,160.00
96T*50$19,200.00
Antigen:
Transforming growth factor beta-1 proprotein
Synonyms: TGFB1_HUMAN; A8K792; P01137; Q9UCG4
Host:Mouse
Reactivity:Human
Application:Western Blotting; ELISA
Isotype:IgG1
Clonality:Monoclonal
Aliases:Cartilage-inducing factor; CED; Differentiation inhibiting factor; DPD1; LAP; Latency-associated peptide; Prepro transforming growth factor beta 1; TGF beta 1; TGF beta; TGF beta 1 protein; TGF-beta 1 protein; TGF-beta-1; TGF-beta-5; TGF-beta1; TGFB; Tgfb-1; tgfb1; TGFB1_HUMAN; TGFbeta; TGFbeta1; Transforming Growth Factor b1; Transforming Growth Factor beta 1; Transforming growth factor beta 1a; transforming growth factor beta-1; transforming growth factor, beta 1; Transforming Growth Factor-ß1
50μl$250.00
100μl$350.00
200μl$450.00
Antigen:
Transforming growth factor beta-1 proprotein
Synonyms: TGFB1_HUMAN; A8K792; P01137; Q9UCG4
Host:Mouse
Reactivity:Human
Application:Western Blotting; Immunohistochemistry; ELISA; FCM
Isotype:IgG1
Clonality:Monoclonal
Aliases:Cartilage-inducing factor; CED; Differentiation inhibiting factor; DPD1; LAP; Latency-associated peptide; Prepro transforming growth factor beta 1; TGF beta 1; TGF beta; TGF beta 1 protein; TGF-beta 1 protein; TGF-beta-1; TGF-beta-5; TGF-beta1; TGFB; Tgfb-1; tgfb1; TGFB1_HUMAN; TGFbeta; TGFbeta1; Transforming Growth Factor b1; Transforming Growth Factor beta 1; Transforming growth factor beta 1a; transforming growth factor beta-1; transforming growth factor, beta 1; Transforming Growth Factor-ß1
50μl$250.00
100μl$350.00
200μl$450.00
Antigen:
Transforming growth factor beta-1 proprotein
Synonyms: TGFB1_HUMAN; A8K792; P01137; Q9UCG4
Test method:Colorimetric
TGF-β is capable of producing a variety of effects and virtually all cell types respond to this factor in some way. The inappropriate presence of active TGF-β1 has been implicated in a variety of pathological conditions Because of the necessity for regulating its activity tightly, TGF-β is secreted by cells in the form of an inactive complex. This complex consists of TGF-β1 associated non-covalently with a protein designated the latency associated peptide (LAP). TGF-β1 and LAP represent components of a pro-peptide that is cleaved in a post-golgi compartment prior to secretion. LAP and TGF-β1 each consist of a disulfide-linked homodimer and the association of these two components renders TGF-β1 inactive and inaccessible to anti-TGF-β antibodies.
48T$140.00
96T$220.00
96T*5$1,000.00
Antigen:
Transforming growth factor beta-1 proprotein
Synonyms: TGFB1_HUMAN; A8K792; P01137; Q9UCG4
Aliases:CED; DPD1; LAP; TGF-beta 1; TGFB; TGFbeta; Transforming growth factor beta-1; TGFB1
Preparation method:CHO; Stable Cells
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, differentiation, motility, adhesion and death. TGF-beta 1 positively and negatively regulates many other growth factors. It inhibits the secretion and activity of many other cytokines including interferon-γ, tumor necrosis factor-alpha and various interleukins. It can also decrease the expression levels of cytokine receptors. Meanwhile, TGF-beta 1 also increases the expression of certain cytokines in T cells and promotes their proliferation, particularly if the cells are immature. TGF-beta 1 also inhibits proliferation and stimulates apoptosis of B cells, and plays a role in controlling the expression of antibody, transferrin and MHC class II proteins on immature and mature B cells. As for myeloid cells, TGF-beta 1can inhibit their proliferation and prevent their production of reactive oxygen and nitrogen intermediates. However, as with other cell types, TGF-beta 1 also has the opposite effect on cells of myeloid origin. TGF-beta 1 is a multifunctional protein that controls proliferation, differentiation and other functions in many cell types. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Once cells lose their sensitivity to TGF-beta1-mediated growth inhibition, autocrine TGF-beta signaling can promote tumorigenesis. Elevated levels of TGF-beta1 are often observed in advanced carcinomas, and have been correlated with increased tumor invasiveness and disease progression.
5µg$120.00
20µg$410.00
100µg$1,350.00
1mg$6,240.00
Antigen:
Transforming growth factor beta-1 proprotein
Synonyms: TGFB1_HUMAN; A8K792; P01137; Q9UCG4
Host:Mouse
Reactivity:Mouse; Rat
Application:IHC-P
Isotype:IgG1
Clonality:Monoclonal
30μl$100.00
100μl$220.00
200μl$360.00
Antigen:
Transforming growth factor beta-1 proprotein
Synonyms: TGFB1_HUMAN; A8K792; P01137; Q9UCG4
Host:Mouse
Reactivity:Human; Mouse; Rat
Application:IHC-P
Isotype:IgG1
Clonality:Monoclonal
30μl$100.00
100μl$220.00
200μl$360.00
Antigen:
Transforming growth factor beta-1 proprotein
Synonyms: TGFB1_HUMAN; A8K792; P01137; Q9UCG4
Host:Rabbit
Reactivity:Human; Mouse; Rat
Application:Western Blotting; IHC-P
Isotype:IgG
Clonality:Polyclonal
30μl$100.00
100μl$220.00
200μl$360.00
Antigen:
Transforming growth factor beta-1 proprotein
Synonyms: TGFB1_HUMAN; A8K792; P01137; Q9UCG4
Host:Rabbit
Reactivity:Human; Mouse; Rat
Application:Western Blotting
Isotype:IgG
Clonality:Polyclonal
30μl$100.00
100μl$220.00
200μl$360.00
Antigen:
Transforming growth factor beta-1 proprotein
Synonyms: TGFB1_HUMAN; A8K792; P01137; Q9UCG4
Host:Rabbit
Reactivity:Human; Mouse; Rat
Application:Western Blotting; ELISA
Isotype:IgG
Clonality:Polyclonal
30μl$100.00
100μl$220.00
200μl$360.00
Antigen:
Transforming growth factor beta-1 proprotein
Synonyms: TGFB1_HUMAN; A8K792; P01137; Q9UCG4
Host:Rabbit
Reactivity:Human; Mouse; Rat
Application:Western Blotting; IHC-P; Immunofluorescence; ELISA
Isotype:IgG
Clonality:Polyclonal
30μl$100.00
100μl$220.00
200μl$360.00