Name: GATA4 Antibody
Brand: Affinity Biosciences
Price: 280 USD

AF5245

$280.00

100μl

	100μl -	$280.00
	200μl -	$350.00

RIDACOM Ltd. hotline:

+3592 955 99 98

info@ridacom.com

GATA4 Antibody

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Western blot analysis of extracts from various samples, using GATA4 Antibody. Lane 1: Rat brain...

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Western blot analysis of GATA4 expression in Jurkat cells

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AF5245 staining 293 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then...

Antigen:

Transcription factor GATA-4

Synonyms: GATA-binding factor 4; GATA4_HUMAN; B7ZKX0; B7ZKZ4; P43694; Q3MJ45; Q5IFM8

BioSeek|Uniprot

Host:Rabbit

Reactivity:Human; Mouse; Rat

Application:Western Blotting; ELISA

Isotype:IgG

Clonality:Polyclonal

Aliases:ASD2; GATA 4; GATA binding protein 4; GATA-binding factor 4; gata4; GATA4_HUMAN; MGC126629; Transcription factor GATA 4; Transcription factor GATA-4; Transcription factor GATA4; VSD1

Description:

Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function (PubMed:24000169, PubMed:27984724). In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression (PubMed:27984724). Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity). Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (By similarity). Promotes cardiac myocyte enlargement (PubMed:20081228). Required during testicular development (PubMed:21220346). May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, spingosine-1-phosphate lyase (PubMed:15734735).

Purification:The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Concentration:1mg/ml

Buffer form:Liquid

Storage buffer:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ¡ãC.Stable for 12 months from date of receipt

Specificity:

GATA4 Antibody detects endogenous levels of total GATA4.

Storage conditions:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt.

Product specifications