Abbkine Scientific Co., Ltd.
ABP52623
$100.00
30μl
| 30μl - | $100.00 | |
| 100μl - | $220.00 | |
| 200μl - | $360.00 |
TNF-R2 Polyclonal Antibody
Fig. Western Blot analysis of various cells using TNF-R2 Polyclonal Antibody diluted at 1:1000....Antigen:
Tumor necrosis factor receptor superfamily member 1B
Synonyms: Tumor necrosis factor receptor 2; Tumor necrosis factor receptor type II; p75; p80 TNF-alpha receptor; TNR1B_HUMAN; B1AJZ3; P20333; Q16042; Q6YI29; Q9UIH1
Host:Rabbit
Reactivity:Human; Mouse; Rat
Application:Western Blotting; IHC-P; Immunofluorescence; ELISA
Isotype:IgG
Clonality:Polyclonal
Description:
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:20000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation:Liquid solution
Precautions:
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Alternative:
TNFRSF1B
TNFBR
TNFR2
Tumor necrosis factor receptor superfamily member 1B
Tumor necrosis factor receptor 2
TNF-R2
Tumor necrosis factor receptor type II
TNF-RII
TNFR-II
p75
p80 TNF-alpha receptor
CD antigen CD120b
Etanercept
Buffer form:PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage conditions:Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Delivery conditions:Gel pack with blue ice.
Immunogen:Synthesized peptide derived from the C-terminal region of human TNF-R2. at AA rangle: 350-430
Usage:
Tumor necrosis factor receptor superfamily member 1B encoded by TNFRSF1B is a member of the TNF-receptor superfamily. Tumor necrosis factor receptor superfamily member 1B and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
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