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$100.00
30μl
30μl -$100.00
100μl -$220.00
200μl -$360.00
RIDACOM Ltd. hotline:
TFE3 Polyclonal Antibody
Antigen:
Transcription factor E3
Synonyms: Class E basic helix-loop-helix protein 33; TFE3_HUMAN; A8MZL6; P19532; Q5JU74; Q92757; Q92758; Q99964
Host:Rabbit
Reactivity:Human; Mouse
Application:Western Blotting; IHC-P; ELISA
Isotype:IgG
Clonality:Polyclonal
Description:
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation:Liquid solution
Precautions:
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Alternative:
TFE3
BHLHE33
Transcription factor E3
Class E basic helix-loop-helix protein 33
bHLHe33
Buffer form:PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage conditions:Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Delivery conditions:Gel pack with blue ice.
Immunogen:Synthesized peptide derived from the Internal region of human TFE3. at AA rangle: 70-150
Usage:
TFE3 (transcription factor binding to IGHM enhancer 3)encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. TFE3 may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants.
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