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$100.00
30μl
30μl -$100.00
100μl -$220.00
200μl -$360.00
RIDACOM Ltd. hotline:
Raf-B (phospho Thr753) Polyclonal Antibody
Antigen:
Serine/threonine-protein kinase B-raf
Synonyms: Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1; BRAF_HUMAN; A4D1T4; B6HY61; B6HY62; B6HY63; B6HY64; B6HY65; B6HY66; P15056; Q13878; Q3MIN6; Q9UDP8; Q9Y6T3
Host:Rabbit
Reactivity:Human; Mouse; Rat
Application:Western Blotting; ELISA
Isotype:IgG
Clonality:Polyclonal
Description:
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, ELISA: 1:5000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation:Liquid solution
Precautions:
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Alternative:
BRAF
BRAF1
RAFB1
Serine/threonine-protein kinase B-raf
Proto-oncogene B-Raf
p94
v-Raf murine sarcoma viral oncogene homolog B1
Buffer form:PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage conditions:Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Delivery conditions:Gel pack with blue ice.
Immunogen:Synthesized peptide derived from human Raf-B around the phosphorylation site of T753.
Usage:
BRAF (B-Raf proto-oncogene, serine/threonine kinase)encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in BRAF are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in BRAF have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for BRAF.
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