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$100.00
30μl
30μl -$100.00
100μl -$220.00
200μl -$360.00
RIDACOM Ltd. hotline:
E-cadherin Polyclonal Antibody
Antigen:
Cadherin-1
Synonyms: CAM 120/80; Epithelial cadherin; Uvomorulin; CADH1_HUMAN; A8K1U7; P12830; Q13799; Q14216; Q15855; Q16194; Q4PJ14; Q9UII8
Cadherin-2
Synonyms: CDw325; Neural cadherin; CADH2_HUMAN; A8MWK3; B0YIY6; P19022; Q14923; Q8N173
Cadherin-3
Synonyms: Placental cadherin; CADH3_HUMAN; B2R6F4; P22223; Q05DI6
Cadherin-4
Synonyms: Retinal cadherin; CADH4_HUMAN; B3KWB8; G3V1P8; P55283; Q2M208; Q5VZ44; Q9BZ05
Host:Rabbit
Reactivity:Human; Mouse; Rat
Application:Western Blotting; IHC-P; Immunofluorescence; ELISA
Isotype:IgG
Clonality:Polyclonal
Description:
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:20000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation:Liquid solution
Precautions:
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Alternative:
CDH1
CDHE
UVO
Cadherin-1
CAM 120/80
Epithelial cadherin
E-cadherin
Uvomorulin
CD antigen CD324
CDH2
CDHN
NCAD
Cadherin-2
CDw325
Neural cadherin
N-cadherin
CD antigen CD325
CDH3
CDHP
Cadherin-3
Placental cadherin
P-cadhe
Buffer form:PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage conditions:Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Delivery conditions:Gel pack with blue ice.
Immunogen:Synthesized peptide derived from the C-terminal region of human E-cadherin. at AA rangle: 810-890
Usage:
CDH1 encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in CDH1 are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization.CDH1 is present in a gene cluster with other members of the cadherin family on chromosome 16.
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