Abbkine Scientific Co., Ltd.
ABP57025
$100.00
30μl
| 30μl - | $100.00 | |
| 100μl - | $220.00 | |
| 200μl - | $360.00 |
CD22 Polyclonal Antibody
Fig. Western Blot analysis of 293 cells using CD22 Polyclonal Antibody.Antigen:
B-cell receptor CD22
Synonyms: B-lymphocyte cell adhesion molecule; Sialic acid-binding Ig-like lectin 2; T-cell surface antigen Leu-14; CD22_HUMAN; F5GYU4; F5H7U3; O95699; O95701; O95702; O95703; P20273; Q01665; Q32M46; Q92872; Q92873; Q9UQA6; Q9UQA7; Q9UQA8; Q9UQA9; Q9UQB0; Q9Y2A6
Host:Rabbit
Reactivity:Human
Application:Western Blotting; ELISA
Isotype:IgG
Clonality:Polyclonal
Description:
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, ELISA: 1:40000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation:Liquid solution
Precautions:
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Alternative:
CD22
SIGLEC2
B-cell receptor CD22
B-lymphocyte cell adhesion molecule
BL-CAM
Sialic acid-binding Ig-like lectin 2
Siglec-2
T-cell surface antigen Leu-14
CD antigen CD22
Buffer form:PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage conditions:Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Delivery conditions:Gel pack with blue ice.
Immunogen:Synthesized peptide derived from human CD22 around the non-phosphorylation site of Y807.
Usage:
CD22, also known as Siglec-2 (sialic acid binding Ig-like lectin 2) or BL-CAM (B-lymphocyte cell adhesion molecule), is a 130-140 kDa, B-cell restricted, type I transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. The expression of CD22 is developmentally regulated. It is expressed at low levels in the cytoplasm of pro-B and pre-B cells and present on the cell surface only at mature stages of B-cell differentiation. Cell surface expression is lost during terminal differentiation into plasma cell and after B-cell activation. CD22 is an inhibitory receptor for B-cell receptor (BCR) signalling, preferentially binds to alpha-2,6-linked sialic acid and mediates B-cell B-cell interactions. It plays a crucial role in activation and differentiation of the B-cell.
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