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Assessment of vitamin B12 absorption in tropical sprue utilizing a whole body counter.
Journal: Boletin de la Asociacion Medica de Puerto Rico
May/24/1976
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A long-term survivor with bladder metastasis from renal cell carcinoma.
Journal: International journal of clinical practice
January/30/2000
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Chromosomes and causation of human cancer and leukemia. XIII. An evaluation of karyotypic findings in erythroleukemia.
Journal: Cancer
June/1/1976
Description

This study was an attempt at defining the cytogenetic features of erythroleukemia (EL), particularly as related to the group of AML patients with MAKA (major karyotypic abnormalities), which generally were caused by three or more cellular events of translocation or nondisjunction. Eight of the 17 patients with MAKA had a diagnosis of EL or possible EL. In most cases, MAKA was featured by hypodiploidy, karyotypic instability, and polyploidy in the leukemic cells. The most common abnormalities were loss of B or G group chromosomes and gain of a no. 16 or one or more marker chromosomes. Each of the markers of 2q+, Dq+, mar(A2, st), mar(C12, M), r(?F) and minute metacentric and acentric markers was observed in two or more patients. The extent of polyploidy seemed to be correlated with the proportion of erythroid precursor cells in the marrow and with the karyotypic instability. Since the patients exhibited the same chromosomal features, whether or not they had a diagnosis of EL or possible EL, and since patients without such a diagnosis also had cytologic suggestions of EL, a close relation of MAKA to EL is assumed. It is believed that patients with MAKA constitute one of the three chromosomally classifiable groups of EL.

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Issues involved in the evaluation of velopharyngeal closure.
Journal: The Cleft palate journal
May/24/1976
Description

The development and use of frontal and base-view fluorography have increased the value of cinefluorography in the evaluation of velopharyngeal closure. This paper discusses problems in the fluorographic examination of the closure mechanism, the need for other measures of velopharyngeal closure, and the validation of closure measures. Reliability data are needed for measurements made from frontal and base-view films and tapes. Measures in addition to those of a fluorographic nature are needed for the identification of persons with questionable velopharyngeal closure and for use in the evaluation of training procedures that may contribute to improved use of the velopharyngeal closure mechanism. A pattern of relationships among fluorographic and nonfluorograph measures of velopharyngeal closure can be studied in the validation of both classes of measures.

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[Results of measuring the modulus of elasticity of microorganism cell walls].
Journal: Mikrobiologiia
May/15/1979
Description

The elasticity modulus of Escherichia coli cell walls was found to change in the course of growth of the culture. It decreased in the middle of the exponential phase, apparently as a result of intensification of biosynthetic and related to them transport processes at this period. If the cells were treated with EDTA, their elasticity modulus was lower, by an order of magnitude, than that of the control cell walls. If the cells were treated with lysozyme, the elasticity modulus of their walls decreased by three orders of magnitude. The elasticity modulus of cell walls was less in gram-positive rods than in E. coli. The elasticity modulus of spherical cells cannot be determined using this technique.

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The intensivist and the hospitalist: defining responsibility.
Journal: The hospitalist
November/23/1999
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Morphological effects of rapeseed oil in rats. III. Studies in germ-free rats.
Journal: Acta medica Scandinavica. Supplementum
April/9/1976
Description

The morphological effects on the myocardium of feeding rapeseed oil were compared in conventional and germ-free rats in short-term experiments (10 days). It was concluded that the fatty accumulation in the heart muscle cells occurring in rats fed rapeseed oil was not influenced by the presence or absence of a normal intestinal flora. In long-term experiments (80 days) under similar conditions, the myocardial effects of feeding germ-free rats with conventional rapeseed oil, rapeseed oil from the Canadian cultivar Oro very low in erucic acid, or arachis oil were studied in serial sections. Severe myocardial lesions developed in the group of rats fed conventional rapeseed oil, while in the other two groups the myocardium was completely normal. These results give no support to the theory that other factors than C22:1 acids in rapeseed oil are responsible for the myocardial lesions.

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Effect of cardioselective beta-blockade on heart function and chest pain in acute myocardial infarction.
Journal: Acta medica Scandinavica. Supplementum
April/29/1976
Description

Systolic time intervals and the a/H ratio were recorded in 20 patients with uncomplicated acute myocardial infarction over a period of five days. The initial high heart rate and systolic blood pressure and the short PEP and ICT indicating a sympathetic overactivity were spontaneously normalized during the first week of infarction. LVET was reduced indicating a fall in stroke volume and the a/H ratio was unchanged at the high levels suggestive of elevated preload or LVEDP. In 10 patients with acute myocardial infarction and recurrent chest pain recordings on noninvasive parameters were made before and 30 min after intravenous injection of practolol. In addition, 7 patients with chest pain, classified as acute myocardial infarction, were given practolol. The average dose of practolol was 17.9 mg ranging from 5 to 30 mg. An almost immediate and pronounced relief of pain was observed in all patients and no signs of impaired left ventricular function appeared. The product of systolic blood pressure and heart rate was decreased by practolol and the PEP and the ICT were prolonged to normal values while no changes were seen in LVET and a/H ratio. On 126 occasions practolol was given in dosages ranging from 5 to 30 mg (mean 8 mg) to 75 patients with acute myocardial infarction and recurrent chest pain. A satisfactory pain relief was seen on 108 occasions. It is suggested that an inappropriate sympathetic overactivity is an important factor in provoking recurrent chest pain in acute myocardial infarction. Administration of the beta-adrenergic blocking agent practolol resulted in pain relief due to reduction of heart work and in severity of myocardial ischemia. The beta-blocking agent was well tolerated in the present study. Continuous beta-blockade during the whole hospital stay to patients with acute myocardial infarction seems to be a very attractive therapy in order to preserve the ischemic myocardium and limit the size of infarction.

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Premises for a medical marketplace: a neoconservative's vision of how to transform the health system.
Journal: Health affairs (Project Hope)
April/19/1982
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The battle for control of health care.
Journal: Health affairs (Project Hope)
December/20/1982
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Genetic variation in postfire aspen seedlings in yellowstone national park
Journal: Molecular ecology
January/4/2000
Description

A rare episode of regeneration of aspen (Populus tremuloides Michx.) by seeds occurred in Yellowstone National Park (YNP), Wyoming, USA, following extensive fires that occurred in 1988. In 1997, we sampled 410 aspen seedlings from 23 local populations distributed widely across YNP to determine how genetic diversity varies with elevation, substrate, plant competition, ungulate browsing, and geographical location. We employed 132 randomly amplified polymorphic DNA (RAPD) markers based on six primers to show genetic relationships within and among the postfire aspen seedling populations. Measures of genetic variation, including estimates of percentage polymorphic loci, expected heterozygosity, and Nei's FST, indicated that most of the variation occurred within rather than among local populations. There was no indication of geographical differentiation among sampled populations based on hierarchal estimates of Nei's FST, neighbour-joining, or correlations between genetic distance and geographical distance. Even genetically distant populations shared nearly 90% of the same markers. Within plots, the amount of genetic variation decreased slightly in response to increased percentage vegetative cover, mean seedling basal diameter, and mean seedling height. Geological substrate, density of lodgepole pine (Pinus contorta var. latifolia Dougl.) seedlings, browsing intensity, and elevation were not significantly related to levels of genetic variation within the seedling plots. These data suggest that genetic variation and geographical structure among seedling populations may occur over time as the transition from seedling-dominated stands to clone-dominated stands occurs.

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Evidence for mediating econeurocardiologic mechanisms.
Journal: Occupational medicine (Philadelphia, Pa.)
February/24/2000
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Operational definitions for year 2000 objectives: Priority Area 1, Physical Activity and Fitness.
Journal: Healthy People 2000 statistical notes
April/22/1999
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Pass the tofu tacos. Soy-based foods are disease fighters, but they can taste pretty weird.
Journal: U.S. news & world report
December/19/1999
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Interactions of the duodenal receptors which control gastric emptying.
Journal: Scandinavian journal of gastroenterology. Supplement
February/29/1976
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Disseminated histoplasmosis following prolonged low-dose methotrexate therapy.
Journal: American journal of hematology
January/20/2000
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[Case of myeloblastic leukemia masked by signs of diabetes insipidus].
Journal: Wiadomosci lekarskie (Warsaw, Poland : 1960)
February/8/1976
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Hernia through the foramen of Winslow.
Journal: The Australian and New Zealand journal of surgery
August/1/1976
Description

This is a report of a hernia through the foramen of Winslow in which the right half of the colon was herniated. It was gangrenous and perforated. Following hemicolectomy the patient recovered.

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Six cases of Gilles de la Tourette's syndrome.
Journal: The British journal of psychiatry : the journal of mental science
August/31/1976
Description

Six cases of Gilles de la Tourette's syndrome are discussed in the light of conflicting views on the aetiology of the condition. It is hypothesized that the onset of coprolalia in patients with persistent childhood tics indicates a disturbances of the normal balance between a need for tension relief by swearing and a capacity to control such vocal activity. Some conclusions are drawn on the management of the syndrome by the use of butyrophenones, massed practice of tics, and the promotion of personality development. A flexible approach geared to the individual patient's particular needs is recommended.

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Quantification of anti-D and fetomaternal hemorrhage by flow cytometry.
Journal: Transfusion
February/9/2000
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D-penicillamine-induced crescentic glomerulonephritis in a patient with scleroderma.
Journal: Nephron
May/14/2000
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An inhibitor of the complement-fixation reaction associated with interferon treatment.
Journal: Clinical immunology and immunopathology
August/31/1976
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Oral cancer in the UK: to screen or not to screen.
Journal: Oral oncology
February/7/2000
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[Laparoscopic surgery in colorectal tumors].
Journal: Vestnik khirurgii imeni I. I. Grekova
February/3/2000
Description

The authors describe their first experience with using less invasive laparoscopic methods in patients with tumors of the rectum and the colon. Twelve operative interventions were performed. The method and technique of endovideosurgical operations on the colon are described. The intraoperative and postoperative complications are analyzed. The authors not rich experience with performing laparoscopic interventions on the colon shows the necessity of stepwise and thorough mastering the method and of using strictly individual indications for such operations.

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