Depression
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Publication
Journal: AIDS and Behavior
February/23/2022
Abstract
Mental health comorbidities are prevalent among young Black gay, bisexual, and other men who have sex with men (YB-GBMSM) living with HIV and can adversely impact HIV-related outcomes. We conducted a cross-sectional survey study with 100 YB-GBMSM recruited from two HIV care centers in Atlanta, and constructed multivariable logistic and linear regression models to examine correlates of depression, anxiety, trauma symptoms, and general well-being. In adjusted models, full-time employment was associated with fewer depressive symptoms, while HIV stigma and substance use were associated with higher levels of depressive symptoms. Younger age and full-time employment were negatively associated with severe anxiety, while HIV stigma was positively associated with severe anxiety and trauma symptoms. Trust in physicians, lower HIV stigma, full-time employment, and lack of substance use were associated with higher average general well-being scores. In conclusion, we found high frequency of depressive, anxiety, and trauma-related symptoms among this sample of YB-GBMSM living with HIV. Unemployment, substance use, and HIV stigma emerged as particularly salient correlates of psychological morbidity, suggesting a need for structural and community-level interventions to address mental health in this population.
Keywords: African American; Depression; HIV; Mental health; Sexual and gender minorities.
Publication
Journal: BMC Women's Health
February/23/2022
Abstract
Background: The incidence of depression in human females rises steadily throughout adolescence, a critical period of pubertal maturation marked by increasing levels of gonadal hormones including estrogens and progesterone. These gonadal hormones play a central role in social and emotional development and may also contribute to the increased occurrence of depression in females that begins in early adolescence. In this study, we examine whether and how introducing synthetic estrogen and progestin derivatives through the use of combined hormonal contraceptives (CHC), affects adolescent females' risk for developing depression. We further assess potential links between CHC use and alterations in stress responses and social-emotional functioning.
Methods: Using a longitudinal cohort design, we will follow a sample of adolescent females over the span of three years. Participants will be assessed at three time points: once when they are between 13 and 15 years of age, and at approximately 18 and 36 months after their initial assessment. Each time point will consist of two online sessions during which participants will complete a clinical interview that screens for key symptoms of mental health disorders, along with a series of questionnaires assessing their level of depressive symptoms and history of contraceptive use. They will also complete a standardized social-evaluative stress test and an emotion recognition task, as well as provide saliva samples to allow for assessment of their circulating free cortisol levels.
Discussion: In this study we will assess the effect of CHC use during adolescence on development of Major Depressive Disorder (MDD). We will control for variables previously found to or proposed to partially account for the observed relationship between CHC use and MDD, including socioeconomic status, age of sexual debut, and CHC-related variables including age of first use, reasons for use, and its duration. In particular, we will discover whether CHC use increases depressive symptoms and/or MDD, whether elevated depressive symptoms and/or MDD predict a higher likelihood of starting CHC, or both. Furthermore, this study will allow us to clarify whether alterations in stress reactivity and social-emotional functioning serve as pathways through which CHC use may result in increased risk of depressive symptoms and/or MDD.
Keywords: Birth control; Cortisol; Emotional development; Major depressive disorder; Mental health; Mood disorder; Puberty; Social functioning; Stress reactivity.
Publication
Journal: Advances in Respiratory Medicine
February/23/2022
Abstract
Introduction: Health care workers (HCWs) are directly involved in processes linked with diagnosis, management, and assistance of coronavirus disease-19 (COVID-19) patients which could have direct implications on their physical and emotional health. Emotional aspects of working in an infectious pandemic situation is often neglected in favour of the more obvious physical ramifications. This single point assessment study aimed to explore the factors related to stress, anxiety and depression among HCWs consequent to working in a pandemic.
Material and methods: This was a cross-sectional study involving healthcare workers who were working in COVID-19 inpatient ward, COVID-19 screening area, suspect ward, suspect intensive care unit (ICU) and COVID-19 ICU across four hospitals in India. A web-based survey questionnaire was designed to elicit responses to daily challenges faced by HCWs. The questionnaire was regressed using machine-learning algorithm (Cat Boost) against the standardized Depression, Anxiety and Stress Scale - 21 (DASS 21) which was used to quantify emotional distress experienced by them.
Results: A total of 156 participants were included in this study. As per DASS-21 scoring, severe stress was seen in ∼17% of respondents. We could achieve an R² of 0.28 using our machine-learning model. The major factors responsible for stress were decreased time available for personal needs, increasing age, being posted out of core area of expertise, setting of COVID-19 care, increasing duty hours, increasing duty days, marital status and being a resident physician.
Conclusions: Factors elicited in this study that are associated with stress in HCWs need to be addressed to provide wholesome emotional support to HCWs battling the pandemic. Targeted interventions may result in increased emotional resilience of the health-care system.
Keywords: COVID-19; anxiety; depression; emotional distress; health-care worker; stress.
Publication
Journal: BJPsych Open
February/23/2022
Abstract
Background: Longitudinal studies are needed to examine the association between maternal depression, trauma and childhood mental health in conflict-affected settings.
Aims: To examine maternal depressive symptoms, trauma-related adversities and child mental health by using a longitudinal path model in conflict-affected Timor-Leste.
Method: Women were recruited in pregnancy. At wave 1, 1672 of 1740 eligible women were interviewed (96% response rate). The final sample comprised 1118 women with complete data at all three time points. Women were followed up when the index child was aged 18 months (wave 2) and 36 months (wave 3). Measures included the Edinburgh Postnatal Depression Scale, lifetime traumatic events and the Child Behaviour Checklist. A longitudinal path analysis examined associations cross-sectionally and in a cross-lagged manner across time.
Results: Maternal depressive symptom score was associated with child mental health (cross-sectional association at wave 2, β = 0.35, P < 0.001; cross-sectional association at wave 3, β = 0.33, P < 0.001). The maternal depressive symptom score at wave 1 was associated with child mental health at wave 2 (β = 0.12, P < 0.001), and the maternal depressive symptom score at wave 2 showed an indirect association with child mental health at wave 3 (indirect standardised coefficient 0.23, P < 0.001). There was a time-lagged relationship between child mental health at wave 2 and maternal depression at wave 3 (β = 0.08, P = 0.02).
Conclusions: Maternal depressive symptoms are longitudinally associated with child mental health, and traumatic events play a role. Maternal depression symptoms are also affected by child mental health. Findings suggest the need for skilled assessment for depression, trauma-informed maternity care and parenting support in a post-conflict country such as Timor-Leste.
Keywords: Conflict-affected populations; child mental health; maternal depression; psychological trauma.
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Publication
Journal: Deutsches Ärzteblatt international
February/23/2022
Abstract
Background: Numerous studies have reported an increase in mental disorders during the COVID-19 pandemic, but the exact reasons for this development are not well understood. In this study we investigate whether pandemic-related occupational and financial changes (e.g., reduced working hours, working from home, financial losses) were associated with increased symptoms of depression and anxiety compared with the situation before the pandemic.
Methods: We analyzed data from the German National Cohort (NAKO) Study. Between May and November 2020, 161 849 study participants answered questions on their mental state and social circumstances. Their responses were compared with data from the baseline survey before the pandemic (2014-2019). Linear fixed-effects models were used to determine whether individual changes in the severity of symptoms of depression (PHQ-9) or anxiety (GAD-7) were associated with occupational/financial changes (controlling for various covariates).
Results: The prevalence of moderate or severe symptoms of depression and anxiety increased by 2.4% and 1.5%, respectively, during the COVID-19 pandemic compared with the preceding years. The mean severity of the symptoms rose slightly. A pronounced increase in symptoms was observed among those who became unemployed during the pandemic (+ 1.16 points on the depression scale, 95% confidence interval [0.91; 1.41], range 0-27). Increases were also seen for reduced working hours with no short-time allowance, increased working hours, working from home, insecurity regarding employment, and financial strain. The deterioration in mental health was largely statistically explained by the occupational and financial changes investigated in the model.
Conclusion: Depressive symptoms and anxiety disorders increased slightly in the study population during the first year of the COVID-19 pandemic. Occupational and financial difficulties were an essential contributory factor. These strains should be taken into account both in the care of individual patients and in the planning of targeted prevention measures.
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Publication
Journal: Medicine
February/23/2022
Abstract
Background: The prevalence of depressive symptoms in obese patients is higher than nonobese patients. Evidence shows an improvement of depressive symptoms after bariatric surgery, but this improvement fluctuates 3-4 years after surgery. Some studies report a worsening of depressive symptoms, but that the type of surgery and surgical complications contribute to the high depression rate. Our objective was to assess depressive symptoms in postbariatric surgery patients using an Arabic version of Patient Health Questionnaire-9 (PHQ-9).
Materials and methods: A cross-sectional study was conducted in a tertiary care hospital in Riyadh from January to December 2019 using a validated Arabic version of PHQ-9. The questionnaires sent through Google Survey link to patient phone numbers were registered in an electronic record system. Data analysis was analyzed using SPSS version 23. Frequency and percentages were computed for the categorical variables and mean and standard deviation were calculated for the continuous variables. Chi-square test performed to test for the association between categorical variables and depression and logistic regression analysis were performed to determine the risk factors for development of depression after bariatric surgery.
Results: A total of 152 patients were included in the study. Fifty percent patients did not have depression, 26.3% had mild depression, 15.8% had moderate depression, 7.2% had moderately severe depression, and only one patient (0.7%) had severe depression. Only marital status was significantly associated with depression after bariatric surgery (P = 0.019). Gender, education, marital status, and income when used in the multivariate logistic regression could not predict the incidence of depression.
Conclusion: Using a score of 10 in PHQ-9 as a cutoff, the prevalence of depressive disorder in postbariatric surgery patients was 23.7%, which is similar to the prevalence of nonobese general Saudi population of 20%.
Keywords: Bariatric surgery; Patient Health Questionnaire-9; depression.
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Publication
Journal: Frontiers in Psychology
February/23/2022
Abstract
The psychological effects of COVID-19 have been documented in the past year, but scarce literature exists on the nature of COVID-19 stressors. Using a random split sample of 1199 young adult university students, results of exploratory factor analyses (EFA) identified a four-factor structure in the COVID-19 Stressors Questionnaire (C19SQ), which were labeled Resource Constraints, Social Restrictions, Future Uncertainty, and Health Concerns. This model was supported by a confirmatory factor analysis (CFA) when run on the other split sample of 1139 university students. Higher levels of COVID-19 stress were positively associated with anxiety and depressive symptoms and negatively associated with sleep duration, sleep quality, and the number of exercise days. COVID-19 stress also uniquely predicted poor university adjustment. This study demonstrated the link between COVID-19 stressors and mental and physical health symptoms, thus providing support for conceptualizing the psychological impact of the pandemic as adjustment problems for some individuals.
Keywords: COVID-19; adjustment; anxiety; depression; factor analyses; stressor; young adulthood.
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Publication
Journal: Clinical Gerontologist
February/23/2022
Abstract
Objectives: The current study investigated whether hope and its two components (agency and pathways) acted as protective factors by weakening the relations between perceived burdensomeness, thwarted belongingness, and acquired capability for suicide and suicide risk among older adults.
Methods: A community sample of 594 older Australians aged from 60 to 95 years (Mage = 68.72, SDage = 6.67) completed the Suicidal Behaviors Questionnaire-Revised, Interpersonal Needs Questionnaire-Revised, Acquired Capability for Suicide Scale-Fearlessness about Death Scale, Adult Hope Scale, and Geriatric Depression Scale-short form.
Results: After controlling for depressive symptoms and sociodemographic variables, hope and agency moderated the thwarted belongingness-suicide risk relation, and hope, agency, and pathways moderated the acquired capability for suicide-risk relation.
Conclusions: Hope may play an important role in reducing suicide risk among older adults experiencing thwarted belongingness and who have acquired the capability for suicide. Research is required to identify ways of reducing suicide risk among older adults who experience perceived burdensomeness.
Clinical implications: Increasing hope may reduce suicide risk among older adults experiencing thwarted belongingness and who have acquired the capability for suicide.
Keywords: Suicide; agency; hope; older adults; pathways.
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Publication
Journal: Journal of Family Psychology
February/23/2022
Abstract
Undocumented Latinx immigrants (ULIs) comprise a large segment of the U.S. population, yet they remain at high risk for diminished health outcomes due to increased exposure to adverse experiences and context. Transnational family separation and the distress that accompanies it is an example of a common adverse experience that is chronic and that impacts the lives of many ULIs. However, despite how chronic and central transnationalism is to the lives of ULIs, little is known about its relation to the health outcomes of ULIs. To that end, this study examined the relation between distress due to transnational family separation and the physical and mental health of ULIs. To do so, the study utilized respondent-driven sampling and path analysis methodologies to cross-sectionally examine how distress from transnational separation was related to the physical and mental health of ULIs (n = 229). Results revealed that as distress from transnational family separation increased so too did participant's depressive (β = .25, p < .001), anxiety (β = .18, p = .006), and physical symptoms (β = .24, p < .0001). Distress from transnational family separation was also more strongly related to physical and depressive symptoms than to anxiety symptoms. Considering these results, important systemic changes to our approach to healthcare delivery and access among ULIs communities are needed to promote the well-being of this at-risk population. Recommendations for doing so are discussed. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
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Publication
Journal: Health and Social Care in the Community
February/22/2022
Abstract
Intimate partner violence (IPV) has recently been recognised as a global public health issue that can cause various kinds of long-lasting physical, sexual and psychological health problems. Limited studies are available concerning the relationship between objective and subjective socioeconomic status (SES) and IPV, and the impact of experiencing IPV on health consequences. This is a cross-sectional study aiming to examine the association between objective and subjective SES as risk factors of IPV, and further investigate how they affect health status in adults who experienced IPV. A total of 400 participants were recruited from June to September 2016 among 18 districts in Hong Kong. Results from multiple linear regression showed that having a higher education (adjusted B [aB] = 0.22, 95% CI = 0.01, 0.45), having lower levels of subjective SES (aB = -0.08, 95% CI = -0.15, -0.01), experiencing childhood stress (aB = 0.58, 95% CI = 0.27, 0.89) and being married (aB = 0.60, 95% CI = 0.01, 1.19) were significantly associated with IPV. While employment and household income were not associated with IPV. Participants with higher levels of subjective SES were more likely to report somatic symptom (aB = -0.44, 95% CI = -0.87, -0.02), anxiety (aB = -0.38, 95% CI = -0.72, -0.04) and depressive symptom (aB = -0.52, 95% CI = -0.94, -0.10). Low subjective SES, instead of low objective SES, was found associated with IPV in Chinese adults. A priority for future studies is the confirmation and expansion of subjective SES and its function in clinical measures. Programmes instilling hope and optimism will be helpful to enhance subjective SES and boost physical and mental well-being in IPV survivors.
Keywords: Chinese adults; intimate partner violence; middle age; risk factor; subjective socioeconomic status.
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