Beat the Blues in Pregnancy Study - Transcranial Magnetic Stimulation
Citations
All
Search in:AllTitleAbstractAuthor name
Publications
(5)
Patents
Grants
Pathways
Clinical trials
Publication
Journal: Journal of Women's Health
June/16/2011
Abstract
OBJECTIVE
Despite the data that major depressive disorder (MDD) is common during pregnancy and that pregnant women prefer nonmedication treatment options, there is a paucity of research examining alternative treatments for this special population. We present the results of an open label pilot study examining treatment with transcranial magnetic stimulation (TMS) in pregnant women with MDD.
METHODS
Ten women with MDD in the second or third trimester of pregnancy were treated with 20 sessions of 1-Hz TMS at 100% of motor threshold (MT) to the right dorsolateral prefrontal cortex. The total study dose was 6000 pulses. Antenatal monitoring was performed during treatment sessions 1, 10, and 20.
RESULTS
Seven of ten (70%) subjects responded (decrease ≥50% in Hamilton Depression Rating Scale [HDRS-17] scores). No adverse pregnancy or fetal outcomes were observed. All infants were admitted to the well baby nursery and were discharged with the mother. Mild headache was the only common adverse event and was reported by 4 of 10 (40%) subjects.
CONCLUSIONS
TMS appears to be a promising treatment option for pregnant women who do not wish to take antidepressant medications.
Publication
Journal: Current Psychiatry Reports
October/11/2010
Abstract
Guidelines regarding the treatment of depression during pregnancy were recently published by the American Psychiatric Association and the American College of Obstetricians and Gynecologists. We provide a commentary on these guidelines.
Publication
Journal: Current Psychiatry Reports
February/1/2010
Abstract
The treatment of major depressive disorder during pregnancy is an important but complex clinical topic. Medications, electroconvulsive therapy, and psychotherapy are all reasonable choices, but each has its limitations. In this article, we propose that a novel device technology known as repetitive transcranial magnetic stimulation should be systematically studied as a potential treatment option for women with major depressive disorder during pregnancy.
Publication
Journal: Israel Journal of Psychiatry and Related Sciences
September/7/2011
Publication
Journal: Women's Health
June/20/2011
Abstract
Depression during pregnancy can negatively affect maternal and fetal health. Some women will choose not to take psychotropic medications during pregnancy. This article reviews alternatives to pharmacologic treatments for women suffering from unipolar depression during pregnancy, focusing on exercise therapy, phototherapy, transcranial magnetic stimulation and acupuncture.