Dimethyl Fumarate
Sort
Pubmeds
(415)
Drug or chemical
Dimethyl Fumarate
Description
A fumarate derivative that is used as a DERMATOLOGIC AGENT in the treatment of PSORIASIS and SKIN DISEASES. It also may be used as an IMMUNOSUPPRESSIVE AGENT in the treatment of MULTIPLE SCLEROSIS.
Related with
416
1
1
107
Pubmed
Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis.
Journal: The New England journal of medicine
September/26/2012
Matched by
Dimethyl Fumarate
Authors
| | | | | | | | |
Related with
265
3
2
1
1
1
3
12
Pubmed
Placebo-controlled phase 3 study of oral BG-12 or glatiramer in multiple sclerosis.
Journal: The New England journal of medicine
September/26/2012
Matched by
Dimethyl Fumarate
Authors
| | | | | | | | |
Related with
216
5
2
1
1
1
3
13
Pubmed
Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study.
Journal: Lancet (London, England)
November/9/2008
Matched by
Dimethyl Fumarate
Authors
| | | | | | | | |
Related with
115
3
2
1
1
1
1
17
Pubmed
Fumaric acid esters are effective in chronic experimental autoimmune encephalomyelitis and suppress macrophage infiltration.
Journal: Clinical and experimental immunology
August/6/2006
Matched by
Dimethyl Fumarate
Authors
| | | |
Related with
73
25
6
2
3
3
5
Pubmed
PML in a patient treated with dimethyl fumarate from a compounding pharmacy.
Journal: The New England journal of medicine
May/1/2013
Matched by
Dimethyl Fumarate
Authors
| | | |
Related with
67
3
3
1
5
Pubmed
Dimethylfumarate inhibits microglial and astrocytic inflammation by suppressing the synthesis of nitric oxide, IL-1beta, TNF-alpha and IL-6 in an in-vitro model of brain inflammation.
Journal: Journal of neuroinflammation
June/30/2010
Matched by
Dimethyl Fumarate
Authors
| | | | |
Related with
64
42
11
2
3
3
1
6
Pubmed
Dimethylfumarate is a potent inducer of apoptosis in human T cells.
Journal: The Journal of investigative dermatology
January/28/2004
Matched by
Dimethyl Fumarate
Authors
| | |
Related with
58
6
1
2
1
1
4
Pubmed
Oral fumaric acid esters for the treatment of active multiple sclerosis: an open-label, baseline-controlled pilot study.
Journal: European journal of neurology
September/4/2006
Matched by
Dimethyl Fumarate
Authors
| | | | | | | |
Related with
52
4
1
1
2
1
1
9
Pubmed
PML in a patient with lymphocytopenia treated with dimethyl fumarate.
Journal: The New England journal of medicine
April/13/2015
Matched by
Dimethyl Fumarate
Authors
| |
Related with
52
4
4
1
3
Pubmed
Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway.
Journal: Cell metabolism
July/2/2012
Matched by
Dimethyl Fumarate
Authors
| | | | | | | | |
Related with
51
64
3
4
1
4
1
1
35
Pubmed
Validation of the multiple sensor mechanism of the Keap1-Nrf2 system.
Journal: Free radical biology & medicine
December/20/2012
Matched by
Dimethyl Fumarate
Authors
| | | | | |
Related with
47
47
15
4
4
2
1
7
Pubmed
Effects of dimethyl fumarate on neuroprotection and immunomodulation.
Journal: Journal of neuroinflammation
January/16/2013
Matched by
Dimethyl Fumarate
Authors
| | | | | | | | |
Related with
46
18
3
3
2
2
2
15
Pubmed
PML in a patient without severe lymphocytopenia receiving dimethyl fumarate.
Journal: The New England journal of medicine
April/13/2015
Matched by
Dimethyl Fumarate
Authors
| | | | | | | | |
Related with
44
3
4
1
10
Pubmed
Dimethylfumarate inhibits TNF-induced nuclear entry of NF-kappa B/p65 in human endothelial cells.
Journal: Journal of immunology (Baltimore, Md. : 1950)
May/16/2002
Matched by
Dimethyl Fumarate
Authors
| | | | | | | |
Related with
43
9
1
1
3
9
Pubmed
The anti-inflammatory effects of dimethyl fumarate in astrocytes involve glutathione and haem oxygenase-1.
Journal: ASN neuro
November/28/2011
Matched by
Dimethyl Fumarate
Authors
| | | | | | |
Related with
43
34
8
4
2
8
Pubmed
Efficacy of fumaric acid esters in the R6/2 and YAC128 models of Huntington's disease.
Journal: PloS one
August/1/2011
Matched by
Dimethyl Fumarate
Authors
| | | | | | |
Related with
41
68
3
3
3
1
1
8
Pubmed
Dimethyl fumarate inhibits dendritic cell maturation via nuclear factor κB (NF-κB) and extracellular signal-regulated kinase 1 and 2 (ERK1/2) and mitogen stress-activated kinase 1 (MSK1) signaling.
Journal: The Journal of biological chemistry
November/4/2012
Matched by
Dimethyl Fumarate
Authors
| | | | | | |
Related with
38
47
3
11
2
3
4
1
8
Pubmed
Dimethylfumarate induces immunosuppression via glutathione depletion and subsequent induction of heme oxygenase 1.
Journal: The Journal of investigative dermatology
April/4/2007
Matched by
Dimethyl Fumarate
Authors
| | | | | | |
Related with
35
11
1
3
2
8
Pubmed
Manufacturer's response to case reports of PML.
Journal: The New England journal of medicine
May/1/2013
Matched by
Dimethyl Fumarate
Authors
| |
Related with
35
3
2
1
3
Pubmed
Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE.
Journal: The Journal of clinical investigation
June/15/2014
Matched by
Dimethyl Fumarate
Authors
| | | | | | | | |
Related with
35
25
1
5
2
4
2
1
10
Pubmed
Dimethylfumarate for psoriasis: more than a dietary curiosity.
Journal: Trends in molecular medicine
August/28/2005
Matched by
Dimethyl Fumarate
Authors
|
Related with
32
6
1
1
4
1
1
2
Pubmed
Antipsoriatic effect of fumaric acid derivatives. Results of a multicenter double-blind study in 100 patients.
Journal: Journal of the American Academy of Dermatology
June/20/1994
Matched by
Dimethyl Fumarate
Authors
| | | | | | | | |
Related with
32
4
5
1
1
1
10
Pubmed
Detoxication enzyme inducers modify cytokine production in rat mixed glial cells.
Journal: Journal of neuroimmunology
September/19/2005
Matched by
Dimethyl Fumarate
Authors
| | | | |
Related with
30
11
3
3
2
6
Pubmed
Oral treatment for multiple sclerosis.
Journal: The Lancet. Neurology
December/7/2011
Matched by
Dimethyl Fumarate
Authors
| |
Related with
30
10
1
1
3
load more...