Fertility preservation in patients with BRCA mutations or Lynch syndrome
Journal: 2021/March - International Journal of Gynecological Cancer
Abstract:
Guidelines and expert consensus are lacking on fertility preservation in BRCA mutation carriers and in patients with Lynch syndrome. The safety of fertility preservation in this setting is still a topic of debate and multiple factors need to be carefully considered. The aim of this review was to analyze the reproductive potential of women harboring a genetic mutation affecting the DNA repair system and explore the efficacy and safety of existing fertility preservation strategies in these patients.
Keywords: BRCA1 protein; BRCA2 protein; lynch syndrome II.
Relations:
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Chemicals
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Processes
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