Engraving our first B cell memories into the repertoire
Journal: 2021/October - Trends in Immunology
Memory B cells are central to effective protection against reinfection. Glaros et al. used single-cell techniques to illuminate how activated mouse B cells are diverted into forming memory cells a few days post-immunogenic exposure. Early memory subsets contribute to a crucial goal: building a diverse and agile humoral defense system.
Keywords: activated B cells; germinal center-independent; memory B cell; plasmablasts; single-cell RNA sequencing.
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