The Protein Data Bank
Abstract
The Protein Data Bank (PDB; http://www.rcsb.org/pdb/ ) is the single worldwide archive of structural data of biological macromolecules. This paper describes the goals of the PDB, the systems in place for data deposition and access, how to obtain further information, and near-term plans for the future development of the resource.
ACKNOWLEDGEMENTS
Research Collaboratory for Structural Bioinformatics (RCSB) is a consortium consisting of three institutions: Rutgers University, San Diego Supercomputer Center at University of California, San Diego, and the National Institute of Standards and Technology. The current RCSB PDB staff include the authors indicated and Kyle Burkhardt, Anke Gelbin, Michael Huang, Shri Jain, Rachel Kramer, Nate Macapagal, Victoria Colflesh, Bohdan Schneider, Kata Schneider, Christine Zardecki (Rutgers); Phoebe Fagan, Diane Hancock, Narmada Thanki, Michael Tung, Greg Vasquez (NIST); Peter Arzberger, John Badger, Douglas S. Greer, Michael Gribskov, John Kowalski, Glen Otero, Shawn Strande, Lynn F. Ten Eyck, Kenneth Yoshimoto (UCSD). The continuing support of Ken Breslauer (Rutgers), John Rumble (NIST) and Sid Karin (SDSC) is gratefully acknowledged. Current collaborators contributing to the future development of the PDB are the BioMagResBank, the Cambridge Crystallographic Data Centre, the HIV Protease Database Group, The Institute for Protein Research, Osaka University, National Center for Biotechnology Information, the ReLiBase developers, and the Swiss Institute for Bio-informatics/Glaxo. We are especially grateful to Kim Henrick of the EBI and Steve Bryant at NCBI who have reviewed our files and sent back constructive criticisms. This has helped the PDB to continuously improve its procedures for producing entries. The cooperation of the BNL PDB staff is gratefully acknowledged. Portions of this article will appear in Volume F of the International Tables of Crystallography. This work is supported by grants from the National Science Foundation, the Office of Biology and Environmental Research at the Department of Energy, and two units of the National Institutes of Health: the National Institute of General Medical Sciences and the National Institute of Medicine.
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