By directly incorporating a sub-wavelength amplifier chip into the spoof plasmonic resonator, the quality (Q) factor of the original passive resonator has been significantly increased by several orders of magnitude. The spoof plasmonic resonator is composed of a corrugated ring with a slit whose optimized offset angle φ is 45°, aiming to achieve a better Q-factor. By tuning the bias voltage applied to the amplifier chip that is placed across the slit, the Q factor has been increased from 9.8 to 21000 for the quadrupole mode when a plastic pipe filled with polar liquids is placed upon the resonator. Experiments at the microwave frequencies verify that the amplifier chip could greatly compensate the loss introduced by the polar liquids under investigation, resulting in an ultra-high-Q sensor for the detection of polar liquids.