Evaluation of software-based telephone counseling to enhance medication persistency among patients with multiple sclerosis.
Journal: 2006/May - Journal of the American Pharmacists Association : JAPhA
ISSN: 1544-3191
PUBMED: 16128502
Abstract:
OBJECTIVE
To evaluate the effect of a software-supported intervention based on the Transtheoretical Model of Change and motivational interviewing on decreasing discontinuation (or increasing persistency) of Avonex (interferon beta-1a--Biogen), a medication for treatment of multiple sclerosis (MS).
METHODS
Randomized controlled experimental design comparison of software-based telephone counseling (intervention group) and standard care (control group).
METHODS
United States.
METHODS
366 patients with MS.
METHODS
Software-based telephone counseling.
METHODS
Discontinuation of Avonex treatment and movement among stages of the Transtheoretical Model of Change.
RESULTS
Patients in the software intervention group demonstrated a statistically significantly lower proportion of Avonex treatment (1.2%) discontinuation than the standard care group (8.7%). In addition, stage movement away from discontinuation of Avonex (i.e., toward continuation of therapy) was significantly higher in the treatment group.
CONCLUSIONS
The Transtheoretical Model of Change constructs and motivational interviewing processes were effectively incorporated into a software-based intervention program, and this significantly decreased the proportion of patients who discontinued treatment of MS with Avonex. The integration of behavioral theory with information systems offers a promising approach for pharmacists and other providers to promote medication persistency.
Relations:
Citations
(16)
Diseases
(1)
Drugs
(1)
Chemicals
(1)
Organisms
(1)
Affiliates
(1)
Similar articles
Articles by the same authors
Discussion board
Collaboration tool especially designed for Life Science professionals.Drag-and-drop any entity to your messages.