[Advances in the Study of the Effects of Video-assisted Thoracoscopic Segmentectomy on Pulmonary Function].
Journal: 2019/August - Chinese Journal of Lung Cancer
ISSN: 1999-6187
Abstract:
The National Comprehensive Cancer Network (NCCN) clinical practice guideline of non-small cell lung cancer (NSCLC) in 2018 points out that anatomic pulmonary resection is a preferred option for early stage NSCLC. With the development of video-assisted thoracoscopy, minimally invasive thoracic surgery represented by thoracoscopy has been widely used in clinical practice. Video-assisted thoracoscopic segmentectomy has become one of the treatment options for early stage NSCLC. Clinical studies have found that sublobar resection can achieve similar results and preserve more pulmonary function in the treatment of early stage NSCLC compared with lobectomy, but the changes of pulmonary function after segmentectomy are still controversial. This article focuses on the research progress of pulmonary function changes in NSCLC patients after video-assisted thoracoscopic segmentectomy. .
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Zhongguo Fei Ai Za Zhi 22(8): 537-540

胸腔镜肺段切除术对肺功能影响的研究进展

100021 北京,国家癌症中心,国家肿瘤临床医学研究中心,中国医学科学院北京协和医学院肿瘤医院胸外科, Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China,
高 禹舜 (Yushun GAO): moc.qq@9595276101
高禹舜, Yushun GAO, E-mail: moc.qq@9595276101
高 禹舜 (Yushun GAO): moc.qq@9595276101
Received 2019 Jan 30; Revised 2019 Mar 10; Accepted 2019 Mar 27.

Abstract

2018年美国国立综合癌症网络关于非小细胞肺癌(non-small cell lung cancer, NSCLC)指南指出,对于早期NSCLC,解剖性肺叶切除为首选方案。随着电视胸腔镜技术的发展,以胸腔镜为代表的胸外科微创手术在临床得到了广泛应用。胸腔镜肺段切除术已经成为早期NSCLC的治疗方案之一。临床研究发现相较于肺叶切除,亚肺叶切除在早期NSCLC治疗中也可取得相似的结果并保留更多的肺功能,但肺段切除术后患者肺功能的改变尚存争议。本文将重点对胸腔镜肺段切除术后患者肺功能改变的研究进展做一综述。

Keywords: 肺肿瘤, 肺段切除术, 肺功能, 电视胸腔镜
Abstract

Abstract

The National Comprehensive Cancer Network (NCCN) clinical practice guideline of non-small cell lung cancer (NSCLC) in 2018 points out that anatomic pulmonary resection is a preferred option for early stage NSCLC. With the development of video-assisted thoracoscopy, minimally invasive thoracic surgery represented by thoracoscopy has been widely used in clinical practice. Video-assisted thoracoscopic segmentectomy has become one of the treatment options for early stage NSCLC. Clinical studies have found that sublobar resection can achieve similar results and preserve more pulmonary function in the treatment of early stage NSCLC compared with lobectomy, but the changes of pulmonary function after segmentectomy are still controversial. This article focuses on the research progress of pulmonary function changes in NSCLC patients after video-assisted thoracoscopic segmentectomy.

Keywords: Lung neoplasms, Segmentectomy, Pulmonary function, Video-assisted thoracoscopy
Abstract

全球范围内肺癌仍然是所有癌症中发病率及死亡率最高的肿瘤,2018年据估计世界上新发肺癌210万例,死于肺癌的患者共180万例1]。随着影像学技术发展,胸部计算机断层扫描(computed tomography, CT)检查可以更早的发现肺部病变,尤其是肺部磨玻璃结节,这导致了外科医生开始考虑能否通过亚肺叶切除实现肿瘤的完全切除。近年来,已经有相关研究2, 3]表明,与标准的肺叶切除相比,亚肺叶切除可使患者获得相似的预后,同时有大量研究表明其在患者术后肺功能保留及恢复方面的优势。随着胸腔镜手术(video-assisted thoracoscopic surgery, VATS)技术的发展,通过胸腔镜微创方法进行非小细胞肺癌(non-small cell lung cancer, NSCLC)切除越来越受欢迎。通过胸腔镜行肺叶及肺段切除术的比例也大大增加,从2007年的11.6%到2015年其应用率已达60.6%。本文将从电视胸腔镜肺段切除的手术适应证、胸腔镜肺段切除术对肺功能的影响、肺段切除术后肺功能代偿及展望四个方面对目前研究进展做一综述。

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